demonstrated that ZSCAN16 (Zinc Finger and SCAN Domain Containing 16) promoted proliferation, migration and invasion of bladder cancer cells via regulating NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells), AKT and mTOR (mechanistic target of rapamycin kinase) [26]. The gene discussed is NFKB1; the disease is urinary bladder cancer.