Subsequently, the correlation between MCM8 expression and clinical characteristics was evaluated using the Mann–Whitney U analysis and the Pearson correlation analysis, which demonstrated that MCM8 expression was positively correlated with pathological grade with a P value of 0.001 (Table 2, Table 3), yet no significant correlation was observed between MCM8 expression and age, gender, tumor size, lymphadenopathy, stage or T Infiltrate (Table 2). Here, MCM8 is linked to neoplasm.