FASLG and infection: In contrast, the main impaired functions, even after 22 days of chronic stress [100, 105], were as follows: (1) cytotoxic mediators, such as interferon (IFN)‐γ2b, Fas ligand (FasL), NK lysin and granzyme; (2) IL‐12 and Tbet, which are responsible for Th1 cell proliferation and maturation, which mediates host defence against intracellular pathogens [106, 107, 108]; and (3) IL‐8, which attracts leucocytes to the infection site [109].