Based on the bivariate regression analysis, history of symptoms of STI, history of hospital admission, history of participation at a traditional birth, family history of HBV, multiple sexual partners, sexual intercourse without a condom, baseline viral load, current CD4 count, duration in ART, WHO clinical staging, presence of OIS, and a baseline Haemoglobin level of anemia had a p-value of less than 0.25, and were entered into the final model (Table 4). The gene discussed is CD4; the disease is sexually transmitted disease.