COL3A1 and pelvic organ prolapse: Generally, positive finding between pelvic organ prolapse and COL3A1 rs1800255 polymorphism was only found in Caucasian population by allele contrast (A vs. G: OR = 1.34, 95%CI = 1.03–1.74, P = 0.030, Fig 1), homozygote comparison (AA vs. GG: OR = 3.25, 95%CI = 1.39–7.59, P = 0.006, Fig 2), and recessive genetic model (AA vs. GG/GA: OR = 3.22, 95%CI = 1.40–7.42, P = 0.006, Fig 3).