Using ROC curve to assesses the abilities of individual CSF biomarkers to indicate stroke among children with TBM at baseline, we obtained the area under the ROC curve (AUC) above 0.70 for lipocalin-2, sP-selectin, glial cell-derived neurotrophic factor (GDNF), sVCAM-1, sRAGE, apolipoprotein CIII, MMP-1, MMP-7, d-dimer, myoglobin, BNDF, complement factor H, PDGF-AB/BB, CXCL10, MIP-1α, ADAMTS13, SAA, PEDF, A1AT, MIP-1β, sICAM-1, apolipoprotein AI, PDGF-AA, and GM-CSF (S2 Table). The gene discussed is ADAMTS13; the disease is Stroke.