Our findings suggested the involvement of proteins associated with thrombus formation (such as D-dimer and ADAMTS13) [24, 25], proteins associated with acute phase of ischemia (such as lipocalin-2, IP-10 and SAA) [26, 27], and angiogenic markers such as platelet derived growth factor (PDGF)-AA). The gene discussed is LCN2; the disease is ischemia.