The AUCs for lipocalin-2, sP-selectin, glial cell-derived neurotrophic factor (GDNF), sVCAM-1, sRAGE, MMP-7, D-dimer, MMP-1, Apolipoprotein CIII, myoglobin and BNDF were ≥0.75 in predicting stroke amongst children with TBM (Table 2, Fig 3). The gene discussed is AGER; the disease is Stroke.