TNF and hepatocellular carcinoma: The KEGG analysis suggested that these HCC-specific EMT genes were mainly involved in pathways associated with cancer, phosphatidylinositol-3-kinase (PI3K)/Akt signaling, focal adhesion, regulation of stem cell pluripotency, IL-17 signaling, transcriptional misregulation in cancer, Wnt signaling, and TNF signaling (Figure 1F).