DCT and vitiligo: It is possible that initial melanocyte destruction mediated by the transferred cells facilitated antigen release and a broadening of the anti-melanocyte response to include endogenous T cells; nevertheless, limited studies using irrelevant TCR transgenic mice (P14) as recipients showed that Trp2/Kb-specific donor cells from Dct-/- mice were still able to induce vitiligo in this setting (Figure 6—figure supplement 2A,B).