While there is evidence that pro-IL-1 and pro-IL-18 are produced during toxoplasmosis (Hunter et al., 1993; Zediak and Hunter, 2003), several studies have concluded that T. gondii does not readily activate inflammasomes and there is evidence that Toxoplasma suppresses inflammasome activity (Ewald et al., 2014; Lima et al., 2018; Liu et al., 2019). This evidence concerns the gene IL18 and toxoplasmosis.