While on the other hand, the treatment group of the cancer tissue with PFT-HSA-TFT-Cy7 and PFT-Hcy-HSA-Cy7 shows a significant decrease in level of TNF-α mRNA, with an average decrease in fold change as 1.9-fold and 2.3-fold at 1 μM and 1.5-fold and 1.9-fold at 3 μM with respect to their controls (Figure 6(a)). This evidence concerns the gene TNF and cancer.