Considering the role of TME in tumor occurrence and development and its prognostic impact, we used three data sets (i.e., GSE114727-inDrop, BRCA_GSE110686, and BRCA_GSE114727_10X) in the TISCH database to analyze the expression of NSUN2 and NSUN6 in TME-related cells. This evidence concerns the gene NSUN6 and neoplasm.