TRPV1 and central nervous system cancer: In particular, a study performed by Nabissi and coworkers has shown that GBM and glioma stem-like cells (GSC) selectively express the TRPV1 5′-untranslated region (5′UTR) variant three (TRPV1v3), one of the four variants resulting from alternative first exon splicing (Nabissi et al., 2016).