Interestingly, miR-204 is an intronic miRNA located between exons 7 and 8 of the TRPM3 gene and its loss in glioma, due to the high methylation of its host gene TRPM3, is associated with an enhancement in cell migration and cellular stemness (Ying et al., 2013) questioning the direct role of TRPM3 and the indirect regulatory functions of miR-204 via its target genes. The gene discussed is TRPM3; the disease is central nervous system cancer.