In BALB/cAnN mice, the expression of CTLA, FASL, GZMa, IDO1, IL-10 and TRAIL was increased on day 5 post-infection, but this profile changed on day 30 post-infection, when FASL expression returned to basal levels, the relative expression of CD39, CD73, FAS, IL-12a, PRF1, PDL1, PDL2, and TGFβ increased, and the expression of IDO1, GZMa, IL-10, and TRAIL remained high. The gene discussed is CD274; the disease is infection.