PKM and cancer: Nevertheless, by virtue of potential effects of other glycolytic enzymes such as pyruvate kinase M2 (PKM2), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and triose phosphate isomerase (TPI) on EMT in cancer cell metabolism (51), future research on pancreatic cancer as well as other carcinomas should investigate their glycosylated forms and effects of these forms on pancreatic cancer progression.