NFKB1 and neoplasm: Furthermore, we discover epithelial-mesenchymal transition signaling (49), TNFαsignaling via NF-κB (50), IL-2/STAT5 signaling (36), interferonγ response signaling and some other pathways are activated in high risk group, most of which trigger tumor cells malignant progression, immune evasion, metastasis and poor prognosis.