These five genes have comparatively higher fold changes, i.e., the expressions and fold changes for SPNS1, PTPN6, CD247, FOS, and PIK3R5 are -5.68, -1.65, 2.72, 1.58, and 2.61, respectively, in the case of T2D. The gene discussed is PIK3R5; the disease is type 2 diabetes mellitus.