Compared to patients with non-PolyVD and IL-6 < 2.64 pg/ml (group 1), patients with PolyVD and IL-6 ≥ 2.64 pg/ml (group 4) were older, had more females, smoked and drank less, and had higher proportions of hypertension, DM, dyslipidemia, AF, previous IS, infection, NIHSS score, and medication usage. Here, IL6 is linked to atrial fibrillation.