APOE and diabetes mellitus: Our findings for the associations of APOE genotypes with diabetes and HbA1c are internally consistent and consistent with the recent PheWAS14, but are inconsistent with a previous meta-analysis mainly in Asians suggesting ε4 carriers had higher risk of diabetes than ε3ε3 carriers28, and with a cross-population meta-analysis suggesting ε2 carriers had higher risk than others50.