Our data from transfection experiments with hsa-miR-126-3p mimic and inhibitors suggested that hsa-miR-126-3p reversed catabolic responses and reduced phosphorylation levels of Erk1/2, p38MAPK, and PI3K/AKT, which were induced by IL-1β treatment in OA-CH. This evidence concerns the gene MAPK3 and cyclic hematopoiesis.