The WHO recommends a method of surveillance [25] that uses results from a combination of HRP2-based RDT with a pan-LDH RDT, Pf-LDH RDT or smear microscopy on clinical malaria cases with HRP2 false negative RDT result as an initial trigger for widespread hrp2/hrp3 deletion surveillance. Here, HDGFL2 is linked to malaria.