We next conducted univariate Cox analysis for 77 TCGA CN-AML patients, including 17 variables (HSPA8 expression, age, gender, WBC counting, BM-blast, hemoglobin, platelet counting and genes mutation (FLT3, KRAS, CEBPA, TET2, TP53, NRAS, IDH1, IDH2, RUNX1, NPM1, mutation vs. wild type)). This evidence concerns the gene NRAS and acute myeloid leukemia.