Due to its variable sensitivity (up to 1 × 10−3), ASqPCR obtained superior results in highly infiltrated specimens, as BM aspirates (mainly enriched in tumor content by CD19+ cells selection, not routinely practiced in many diagnostic laboratories) [27], while did not perform concordantly well in unsorted BM or peripheral blood (PB) from WM and especially in IgM-MGUS samples (Table S1). The gene discussed is CD19; the disease is neoplasm.