To benchmark the JMJD6 regulon as a prognostic marker for progressive/recurrent PCa, three reported independent signatures were selected for comparison: two androgen receptor related signatures (namely TMEFF2 regulated cell cycle related gene signature [11] and the bromodomain related 10-genes signature [12]) as well as a 28-gene hypoxia signature [13]. Here, JMJD6 is linked to posterior cortical atrophy.