A small sample of tumor culture medium was supplemented with soluble CXCL12 at a concentration of 100 nM to enhance immune cell migration and some CD276-CAR NK-92 cells were pre-treated with prostaglandin E2 (PGE2) at a concentration of 5.7 μM in order to block migration [64,65]. The gene discussed is CXCL12; the disease is neoplasm.