Of these, mucin-type O-glycan biosynthesis (p = 7.31 × 10−5), Hippo signaling pathway (p = 1.09 × 10−4), FoxO signaling pathway ( p = 3.62 × 10−4), PI3K-Akt signaling pathway (p = 3.75 × 10−3), focal adhesion (p = 6.13 × 10−3), adherens junction (p = 1.49 × 10−2), Rap1 signaling pathway (p = 1.53 × 10−2), and transforming growth factor-beta (TGF-β) signaling pathway (p = 2.21 × 10−2) were the most prominent pathways rich in quantile with differential EV miRNA patterns, suggesting that these biological pathways are involved in CRS development (Figure 3B,C). The gene discussed is AKT1; the disease is congenital rubella syndrome.