We found that U87MG GBM cells transfected with SRSF1 expression vector migrated more than controls and that GBM tissue samples with high SRSF1 immunohistochemical expression had higher MVD value than those with SRSF1 low expression (median values: 114/mm2 vs. 67/mm2), confirming the pro-angiogenic function of SRSF1. The gene discussed is SRSF1; the disease is glioblastoma.