CPS1 and spondylo-ocular syndrome: Kallianpur et al. [35] found an association of the hemostatic iron regulator variant rs1800562(A > G) (HFE; RR 3.7; CI 1.2–12.1) and carbamoyl phosphate synthetase I variant rs7422339(CC vs. AC/AA) (CPS1, no RR; p = 0.04) with SOS in 166 adult patients undergoing autologous or allogeneic HSCT for various malignancies.