However, this is a very common oversight, and the presence of TGFβ in endothelial cells, vascular smooth muscle cells (VSMCs), myofibroblasts, macrophages and hematopoietic cells, but not blood platelets, has commonly been used to implicate TGFβ in the pathogenesis of cardiovascular diseases, such as coronary artery disease or hypertension. This evidence concerns the gene TGFB1 and cardiovascular disorder.