It should be mentioned that the process of liver fibrosis may result not only from the interaction of platelets, and platelet TGFβ, with liver cells including hepatocytes, but also with other types of cells that build the liver, such as residual liver macrophages or hepatic endothelial cells, which show the ability to internalize platelets [74,75]. This evidence concerns the gene TGFB1 and Hepatic fibrosis.