In 2014, recessive DNAJC3 mutations were linked to Diabetes mellitus complicated by multisystemic neurodegeneration including ataxia, upper-motor-neuron damage, peripheral neuropathy, sensorineural hearing loss, and cerebral atrophy [261] (MIM: 616192) and a further clinical and molecular genetic study confirmed the phenotype associated with recessive loss of function mutations within DNAJC3 [292]. The gene discussed is DNAJC3; the disease is peripheral neuropathy.