PRKN and Parkinson disease: Mutations in the α-synuclein gene (SNCA), in the leucine-rich repeat kinase 2 gene (LRRK2), and Vacuolar protein sorting ortholog 35 (VPS35) account for the autosomal-dominant PD forms, while mutations in PTEN-induced putative kinase 1 (PINK1), Parkin (PRKN), and protein deglycase DJ-1 (PARK7) are responsible for the autosomal recessive forms [56].