Among them, we focused on those related with DDR pathways, including those classified by gene ontology as ATR, Fanconi Anemia, ATM, and BARD1 pathways, where a strong enrichment score (ES) and a low false discovery rate (FDR) was observed (ATR pathway; NES: 1,93; FDR: 0.002; Fanconi Anemia pathway; NES: 1.869; FDR: 0.004; BARD1 pathway; NES: 1.78; FDR: 0.013 ATM pathway; NES: 1.746; FDR: 0.015 ) (Figure 1B). This evidence concerns the gene ATR and Fanconi anemia.