AVP and invasive breast carcinoma: Many risk factors are associated with the development of BrCa, but the causal mechanism cannot be directly linked to a single one of them which include: age, familial history of BrCa, personal history of benign breast biopsy (atypical ductal and lobular hyperplasia—ADH and ALH), breast density, factors associated with lifestyle (cigarette smoking, alcohol use, dietary fat intake, and postmenopausal obesity), and reproductive factors (nulliparity, late age of first live birth) [2].