We discovered a novel STR at variable length in nTregs from WT and CD8−/− mice upstream of the TSS of Il-6. Due to their association with human disease including asthma and atopic disease [55,56,57], the biological contribution of STRs has been studied intensively, leading to new paradigms to improve our current understanding of their effect on genome structure and function [58]. The gene discussed is CD8A; the disease is asthma.