ADORA2A and neoplasm: When we measured tumor volume and body weight as described in Section 2, the tumor volumes were found to be significantly increased in the RT-R-4T1-EV group compared to the 4T1-EV group and notably reduced in the 4T1-A2AR-shRNA and RT-R-4T1-A2AR-shRNA groups compared to the EV group (Figure 6B–D).