Another differentially expressed transcript, that is robustly associated to NUP98/NSD1 fusion and to PIF status, is CDCP1 (CUB-Domain Containing Protein 1), also known as SIMA135, gp140, CD318 and Trask, which is upregulated in other malignancies including breast, colon and lung cancers, but only few studies evaluated its expression and role in hematological tumors [33]. The gene discussed is NUP98; the disease is lung carcinoma.