In order to further validate the obtained results, we exploited the recent availability of novel RNA-Seq data from the collaborative study between the Children’s Oncology Group (COG) and European AML study groups, aimed to define gene expression profile associated to NUP98-KDM5A and NUP98-NSD1 rearrangements in childhood AML. Here, NUP98 is linked to acute myeloid leukemia.