ARHGEF10 and autism: Interestingly, DLGAP2, a “synaptic” gene associated with autism [13], is the only gene lost in Patient 4, who carries the smallest microdeletion (71.79 kb) and presents behavioral issues (Table 1); ARHGEF10 is the only gene lost in the second smallest microdeletion (83.33 kb), found in Patient 7, who also displays a hyperkinetic behavior (Table 1).