This expression pattern was also observed in PCa tissues for Gleason scores (GS) of 6–9 (p < 0.001) with regard to normal tissues, as shown in Figure 5B. Regarding the molecular signature of PCa tissues, the transcript was upregulated in those tissues which have ERG, ETV1, and ETV4 fusion and SPOP mutations (p < 0.01), as depicted in Figure 5C. Although GS 10 and other molecular features had no significant differences, the number of patients is comparably limited. The gene discussed is SPOP; the disease is posterior cortical atrophy.