In comparison to BPH1 cells, tmtc3 transcript was upregulated (p < 0.05) in most of the PCa cells except LNCaP cells where tmtc4 was markedly upregulated in the studied PCa cells (p < 0.001), as shown in Figure 1B. Thus, our next experiments focused on only TMTC4 protein expression in cells and human tissues. Here, TMTC3 is linked to posterior cortical atrophy.