Traditional cardiometabolic risk factors including hypertension, diabetes, dyslipidemia, and smoking [8,9], and non-traditional cardiometabolic risk factors including abdominal obesity, insulin resistance, lipid profile, arterial stiffness, renal markers, and high-sensitivity C-reactive protein (hs-CRP; as a marker of inflammation [10,11]) levels [8,12,13] are both expensive and difficult to measure outside a clinical environment [14]. The gene discussed is CRP; the disease is Insulin resistance.