By uploading GTF3A coexpressed genes from the TCGA-CRC dataset into the MetaCore, we revealed that cell cycle-related pathways and networks including “DNA damage_ATM/ATR regulation of G2/M checkpoint: cytoplasmic signaling”, “Development_Positive regulation of WNT/Beta-catenin signaling in the cytoplasm”, “Putative roles of SETDB1 and PLU-1 in melanoma”, “Proteolysis_Putative ubiquitin pathway”, and “Immune response_BAFF-induced non-canonical NF-κB signaling” (Figure 7). The gene discussed is SETDB1; the disease is melanoma.