The μSPE microchip developed by Campos et al. composed by arrays of micropillars to detect ctDNA showed efficacy for clinical disease detection of KRAS mutation gene in cfDNA extracted from plasma samples of 3 NSCLC and 5 colorectal cancer patients with the device, with less processing steps than the commercial kits [107]. This evidence concerns the gene KRAS and non-small cell lung carcinoma.