Analysis of potential target genes of MYC involved in the KJ-Pyr-9-induced survival decrease revealed a decrease of cyclin D1 (CCND1) after 24 h treatment with 20 μM KJ-Pyr-9 for BKZ-6 and BKZ-8 as representative cell populations for squamous cell carcinoma- and adenocarcinoma-derived LCSC-like cells. This evidence concerns the gene CCND1 and squamous cell carcinoma.