Accordingly, analysis of cell survival after TNF-α-stimulation revealed no change in survival of AC-derived LCSC-like cells, but a significant reduction in survival of SCC-derived LCSC-like cells, reflecting differences in the dependence on TNF-α/NF-κB-mediated pathways between NSCLC-derived LCSC-like cells. This evidence concerns the gene TNF and non-small cell lung carcinoma.