PRKN and Parkinson disease: Variants in a variety of genes have been reported to be associated with PD, including SNCA (encoding α-synuclein), ADH1C, DJ-1, EIF4G1, FBXO7, GBA/GBAP1, GIGYF2, HTRA2, LRRK2 [114], MAPT, PARK2, PARK7 [115], PRKN, PINK1, PLA2G6, UCHL1, and VPS35 [116].