Two studies evaluated tumor-infiltrating CD4+ cells (CD4+ T cells counts/mm2 of tumor area) dichotomized at the median [9,36], another study stromal-infiltrating CD3+ cells (CD3+ T cells counts/mm2 of stromal area) dichotomized at the median [37], and in another study an Immunoscore higher or equal to 2 [41]. The gene discussed is CD4; the disease is neoplasm.