We detected by IHC the markers for autophagy (LC3 and p62) and for activated stromal fibroblasts (CAFs; with α-SMA) and for IL-6 in tumor specimens at Month 1 and 6 after cholangiocarcinogenesis, i.e., at early and late stages of stromal fibrosis. The gene discussed is MAP1LC3A; the disease is neoplasm.