We found no statistically significant association between OS and gender (p = 0.438), concomitant CIS (p = 0.324), pT stage (p = 0.337), lymph node involvement (p = 0.383), distant metastases (p = 0.380), positive surgical resection margins (p = 0.497), or tumor recurrence (p = 0.389), regardless of PD-L1 expression (data not shown). The gene discussed is CD274; the disease is in situ carcinoma.