CD4 and neoplasm: The observation that an IFN-γ neutralising antibody can block CXCR3+CD4+ T cell infiltration into the tumour mass (Figure 5E), but an antibody that blocks the binding of CXCL10 and CXCL11 to CXCR3 cannot (Figure 7D, suggests that while CXCL10 is important for the infiltration of CD8+ T cells into SCC, different chemokines may influence the migration of CD4+ T cells into SCC.