The following cutoff values positively correlate with the severity grade of AP: Ranson ≥ 3, Glasgow ≥ 3, MOSS ≥ 5, BISAP ≥ 2, APACHE II ≥ 8, CTSI ≥ 5, procalcitonin ≥ 0.5 ng/mL, CRP ≥ 150 mg/L, and IL-6 ≥ 50 pg/mL [8]. The gene discussed is IL6; the disease is alkaline phosphatase measurement.