GPT and Abnormal renal physiology: In addition, patients with central nervous system manifestations [4,8], high levels of alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and creatine kinase (CK) [8], renal dysfunction [9], coagulopathy, high level viremia, and hypercytokinemia were reported to show poor prognosis [10].