STK11 and pancreatic intraductal papillary-mucinous neoplasm: However, based on their findings, they concluded that the lack of β-catenin did not impede the formation of intraductal papillae and their progression to papillary lesions in IPMN, which probably because the activating KrasG12D mutation combined with LKB1 ablation produced more synergistic effects in promoting development of IPMN [53].