RIPK1 and skin disorder: Dermatitis in Sharpincpdm/cpdm mice is driven by TNF/TNFR signalling in keratinocytes and is dependent on the kinase activity of RIPK1, and also partly dependent on NLRP3 inflammasome-mediated IL-1β activity and IL-1 receptor signalling [19,113,140,147,148,149,150].