A study suggested that there was a reduction of ChAT activity and mAChRs binding in the piriform cortex, amygdala, and nucleus basalis, a decrease of AChE activity in the piriform cortex, and a loss of Na+-dependent high-affinity choline uptake in the piriform cortex and amygdala in a kainic acid-induced epilepsy model [30]. Here, CHAT is linked to epilepsy.